Results of a study presented at the American college of cardiology scientific sessions reveal an association between vitamin D (total and bio-available) levels and lower risk of major adverse cardiovascular events including heart failure,stroke,and heart attack.

“Many epidemiological studies have shown that (low) total circulating levels of 25-hydroxyvitamin D (25(OH)D) are strongly associated with poor cardio-vascular outcomes,” note Heidi T.May,PhD,MSPH, and colleagues.”However,85%-90% of circulating vitamin D is bound to vitamin D binding protein or albumin, and levels obtained may not be truly reflective of the vitamin D available to act on target cells.”

Acting on the results of observational studies, the researchers determined levels of total serum 25 (OH) D and 25 (OH)D bound to albumin and vitamin D binding protein in 4,200 men and women.

“our study found that low levels of both total vitamin D and bioavailable vitamin D and bioavailable vitamin D appear to be associated with poor cardiovascular outcomes,”DR.May reported.